Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method

Walid Fathalla

doi:doi:10.11648/j.sjc.20140205.11

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Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method

Walid Fathalla

Published in Science Journal of Chemistry (Volume 2, Issue 5)

Received: 17 November 2014 Accepted: 26 November 2014 Published: 5 December 2014

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Abstract

An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.

Published in	Science Journal of Chemistry (Volume 2, Issue 5)
DOI	10.11648/j.sjc.20140205.11
Page(s)	38-43
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Trichloroacetimidate Method, C-C Bond Formation, C-Nucleophiles, Bezhydryl Derivatives

References

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APA Style

Walid Fathalla. (2014). Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Science Journal of Chemistry, 2(5), 38-43. https://doi.org/10.11648/j.sjc.20140205.11

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ACS Style

Walid Fathalla. Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Sci. J. Chem. 2014, 2(5), 38-43. doi: 10.11648/j.sjc.20140205.11

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AMA Style

Walid Fathalla. Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Sci J Chem. 2014;2(5):38-43. doi: 10.11648/j.sjc.20140205.11

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@article{10.11648/j.sjc.20140205.11,
  author = {Walid Fathalla},
  title = {Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method},
  journal = {Science Journal of Chemistry},
  volume = {2},
  number = {5},
  pages = {38-43},
  doi = {10.11648/j.sjc.20140205.11},
  url = {https://doi.org/10.11648/j.sjc.20140205.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20140205.11},
  abstract = {An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.},
 year = {2014}
}

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TY  - JOUR
T1  - Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method
AU  - Walid Fathalla
Y1  - 2014/12/05
PY  - 2014
N1  - https://doi.org/10.11648/j.sjc.20140205.11
DO  - 10.11648/j.sjc.20140205.11
T2  - Science Journal of Chemistry
JF  - Science Journal of Chemistry
JO  - Science Journal of Chemistry
SP  - 38
EP  - 43
PB  - Science Publishing Group
SN  - 2330-099X
UR  - https://doi.org/10.11648/j.sjc.20140205.11
AB  - An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.
VL  - 2
IS  - 5
ER  -

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Author Information

Walid Fathalla

Department of Mathematics and Physics, Faculty of Engineering, Port-Said University, Port Said, Egypt

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Walid Fathalla. (2014). Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Science Journal of Chemistry, 2(5), 38-43. https://doi.org/10.11648/j.sjc.20140205.11

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ACS Style

Walid Fathalla. Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Sci. J. Chem. 2014, 2(5), 38-43. doi: 10.11648/j.sjc.20140205.11

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AMA Style

Walid Fathalla. Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Sci J Chem. 2014;2(5):38-43. doi: 10.11648/j.sjc.20140205.11

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@article{10.11648/j.sjc.20140205.11,
  author = {Walid Fathalla},
  title = {Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method},
  journal = {Science Journal of Chemistry},
  volume = {2},
  number = {5},
  pages = {38-43},
  doi = {10.11648/j.sjc.20140205.11},
  url = {https://doi.org/10.11648/j.sjc.20140205.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20140205.11},
  abstract = {An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method
AU  - Walid Fathalla
Y1  - 2014/12/05
PY  - 2014
N1  - https://doi.org/10.11648/j.sjc.20140205.11
DO  - 10.11648/j.sjc.20140205.11
T2  - Science Journal of Chemistry
JF  - Science Journal of Chemistry
JO  - Science Journal of Chemistry
SP  - 38
EP  - 43
PB  - Science Publishing Group
SN  - 2330-099X
UR  - https://doi.org/10.11648/j.sjc.20140205.11
AB  - An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.
VL  - 2
IS  - 5
ER  -

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