Special Issue on Bone Marrow Adiposity

Submission Deadline: Feb. 20, 2020

This special issue currently is open for paper submission and guest editor application.

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Special Issue Flyer (PDF)

  • Special Issue Editor
    • Department of Nutrition and Dietetics, Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor,, Malaysia
    Guest Editors play a significant role in a special issue. They maintain the quality of published research and enhance the special issue’s impact. If you would like to be a Guest Editor or recommend a colleague as a Guest Editor of this special issue, please Click here to fulfill the Guest Editor application.
  • Introduction

    Flavonoids intake are associated with a lower risk of aging, including osteoporotic fractures. The mechanisms mediating the effects are not yet understood; among the candidates are modifications of mesenchymal stem cells (MSCs) differentiation. Over the past two decades, extensive research exploring the physiological and therapeutic significance of PPARγ activation has been conducted. PPARγ is induced during the differentiation of preadipocytes and is expressed also in antigen-presenting cells such as dendritic cells and macrophages. An increase in marrow adipocytes is associated with osteoporosis and age-related osteopenia, where in humans up to 90% of the marrow cavity is occupied by adipocytes resulting in the appearance of fatty marrow by the third decade of life. Thus, there is a clinical correlation between the appearance of bone marrow fat and reduced bone forming capacity.
    Furthermore, the reciprocal relationship between osteogenesis and adipogenesis, in combination with the increased adipogenesis during aging and osteoporosis, opens opportunities to decrease adipocyte differentiation, accompanied by an increase of osteoblast formation providing a therapeutic target to prevent further increases in adipocytes formation. Wingless type MMTV integration site family members (WNTs) are a family of secreted glycoproteins acting in autocrine and paracrine fashions to regulate adult tissue homeostasis.
    Aims and Scope:
    1. Bone Marrow Adiposity
    2. Flavonoids
    3. Mesenchymal Stem Cells
    4. Adipocytes
    5. Wnt Signaling Pathway
    6. Osteoporosis and Aging

  • Guidelines for Submission

    Manuscripts can be submitted until the expiry of the deadline. Submissions must be previously unpublished and may not be under consideration elsewhere.

    Papers should be formatted according to the guidelines for authors (see: http://www.ijnfs.org/submission). By submitting your manuscripts to the special issue, you are acknowledging that you accept the rules established for publication of manuscripts, including agreement to pay the Article Processing Charges for the manuscripts. Manuscripts should be submitted electronically through the online manuscript submission system at http://www.sciencepublishinggroup.com/login. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal and will be listed together on the special issue website.

  • Published Papers

    The special issue currently is open for paper submission. Potential authors are humbly requested to submit an electronic copy of their complete manuscript by clicking here.

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