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Predictability of Postprandial Lipidemia by Fasting Values in Young Women

Received: 9 August 2023     Accepted: 2 September 2023     Published: 14 September 2023
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Abstract

For postprandial hyperlipidemia, screening large numbers of subjects by fat-ingestion tests is inconvenient and unrealistic. In the present study, we performed a fat-ingestion test and searched for fasting items to predict postprandial lipidemia. Methods: Healthy young Japanese women (n=54, age 21.1 ± 1.0 y) with apolipoprotein E phenotype 3/3 were enrolled. They ingested fat cream (OFTT cream™, Jomo, Japan; 1 g/kg as cream, 0.35 g/kg as fat). Venous blood samples were taken before (0 h) and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: In multiple regression analyses, the area under the curve (AUC) and the peak of serum triglyceride (TG) were predictable by fasting (f)-TG itself, the AUC of remnant-like particle-TG (RP-TG) was predictable by f-TG and f-RP-TG, the AUC and the peak of remnant lipoprotein-cholesterol (RLP-C) were predictable by f-RLP-C itself, and those of apolipoprotein B-48 (ApoB48) were predictable by f-ApoB48 itself. The AUC and the peak of TG–RP-TG, an index of non-remnant TG, were predictable by f-TG. Conclusion: Postprandial lipidemia may be predictable by the measurement of the set of fasting serum TG, RLP-C, and ApoB48. For daily medical practice, without performing a fat-ingestion test, the set may provide a useful device for predicting postprandial lipidemia.

Published in International Journal of Nutrition and Food Sciences (Volume 12, Issue 5)
DOI 10.11648/j.ijnfs.20231205.11
Page(s) 116-122
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Predictability, Fat-Ingestion Test, Postprandial Lipidemia, Triglyceride, Remnant Lipoprotein-Cholesterol, Apolipoprotein B-48, Women

References
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[2] Takeuchi K, Kazumura K, Kuzawa K, Hatano Y, Nagai M, Naito M: Effect of fat ingestion on postprandial oxidative status in healthy young women: a pilot study. Journal of Clinical Biochemistry and Nutrition 2023 https://doi.org/10.3164/jcbn.23-50. (Advance online publication)
[3] Nabeno Y, Fukuchi Y, Matsutani Y, Naito M: Influence of aging and menopause on postprandial lipoprotein responses in healthy adult women. Journal of Atherosclerosis and Thrombosis 2007; 14: 142–150.
[4] Mizutani-Watanabe E, Naito M: Remnant indices for estimating postprandial lipidemia in young women. International Journal of Nutrition and Food Sciences 2023; 12: 21–28.
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[14] Wideman L, Kaminsky LA, Whaley MH: Postprandial lipemia in obese men with abdominal fat patterning. Journal of Sports Medicine and Physical Fitness 1996; 36: 204–210.
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Cite This Article
  • APA Style

    Erika Mizutani-Watanabe, Michitaka Naito. (2023). Predictability of Postprandial Lipidemia by Fasting Values in Young Women. International Journal of Nutrition and Food Sciences, 12(5), 116-122. https://doi.org/10.11648/j.ijnfs.20231205.11

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    ACS Style

    Erika Mizutani-Watanabe; Michitaka Naito. Predictability of Postprandial Lipidemia by Fasting Values in Young Women. Int. J. Nutr. Food Sci. 2023, 12(5), 116-122. doi: 10.11648/j.ijnfs.20231205.11

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    AMA Style

    Erika Mizutani-Watanabe, Michitaka Naito. Predictability of Postprandial Lipidemia by Fasting Values in Young Women. Int J Nutr Food Sci. 2023;12(5):116-122. doi: 10.11648/j.ijnfs.20231205.11

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  • @article{10.11648/j.ijnfs.20231205.11,
      author = {Erika Mizutani-Watanabe and Michitaka Naito},
      title = {Predictability of Postprandial Lipidemia by Fasting Values in Young Women},
      journal = {International Journal of Nutrition and Food Sciences},
      volume = {12},
      number = {5},
      pages = {116-122},
      doi = {10.11648/j.ijnfs.20231205.11},
      url = {https://doi.org/10.11648/j.ijnfs.20231205.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20231205.11},
      abstract = {For postprandial hyperlipidemia, screening large numbers of subjects by fat-ingestion tests is inconvenient and unrealistic. In the present study, we performed a fat-ingestion test and searched for fasting items to predict postprandial lipidemia. Methods: Healthy young Japanese women (n=54, age 21.1 ± 1.0 y) with apolipoprotein E phenotype 3/3 were enrolled. They ingested fat cream (OFTT cream™, Jomo, Japan; 1 g/kg as cream, 0.35 g/kg as fat). Venous blood samples were taken before (0 h) and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: In multiple regression analyses, the area under the curve (AUC) and the peak of serum triglyceride (TG) were predictable by fasting (f)-TG itself, the AUC of remnant-like particle-TG (RP-TG) was predictable by f-TG and f-RP-TG, the AUC and the peak of remnant lipoprotein-cholesterol (RLP-C) were predictable by f-RLP-C itself, and those of apolipoprotein B-48 (ApoB48) were predictable by f-ApoB48 itself. The AUC and the peak of TG–RP-TG, an index of non-remnant TG, were predictable by f-TG. Conclusion: Postprandial lipidemia may be predictable by the measurement of the set of fasting serum TG, RLP-C, and ApoB48. For daily medical practice, without performing a fat-ingestion test, the set may provide a useful device for predicting postprandial lipidemia.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Predictability of Postprandial Lipidemia by Fasting Values in Young Women
    AU  - Erika Mizutani-Watanabe
    AU  - Michitaka Naito
    Y1  - 2023/09/14
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ijnfs.20231205.11
    DO  - 10.11648/j.ijnfs.20231205.11
    T2  - International Journal of Nutrition and Food Sciences
    JF  - International Journal of Nutrition and Food Sciences
    JO  - International Journal of Nutrition and Food Sciences
    SP  - 116
    EP  - 122
    PB  - Science Publishing Group
    SN  - 2327-2716
    UR  - https://doi.org/10.11648/j.ijnfs.20231205.11
    AB  - For postprandial hyperlipidemia, screening large numbers of subjects by fat-ingestion tests is inconvenient and unrealistic. In the present study, we performed a fat-ingestion test and searched for fasting items to predict postprandial lipidemia. Methods: Healthy young Japanese women (n=54, age 21.1 ± 1.0 y) with apolipoprotein E phenotype 3/3 were enrolled. They ingested fat cream (OFTT cream™, Jomo, Japan; 1 g/kg as cream, 0.35 g/kg as fat). Venous blood samples were taken before (0 h) and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: In multiple regression analyses, the area under the curve (AUC) and the peak of serum triglyceride (TG) were predictable by fasting (f)-TG itself, the AUC of remnant-like particle-TG (RP-TG) was predictable by f-TG and f-RP-TG, the AUC and the peak of remnant lipoprotein-cholesterol (RLP-C) were predictable by f-RLP-C itself, and those of apolipoprotein B-48 (ApoB48) were predictable by f-ApoB48 itself. The AUC and the peak of TG–RP-TG, an index of non-remnant TG, were predictable by f-TG. Conclusion: Postprandial lipidemia may be predictable by the measurement of the set of fasting serum TG, RLP-C, and ApoB48. For daily medical practice, without performing a fat-ingestion test, the set may provide a useful device for predicting postprandial lipidemia.
    VL  - 12
    IS  - 5
    ER  - 

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Author Information
  • Division of Nutrition and Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan

  • Division of Nutrition and Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan

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